Yang Wu

Our review paper will be on the use of biodegradable polymeric drug delivery systems in the treatment of ocular diseases. This will be a fundamental science-oriented paper, focusing on pharmacology, treatment targets and materials science. Therefore those with a background in fundamental science are welcome.

Selection criteria:
-Past experience in fundamental/pharmacology/materials science research
-Knowledge of the following keywords: nanomicelles, nanoparticles, nanosuspensions, nanofiber, nanosphere, nanocapsule, microneedles, microemulsion, liposomes, dendrimers, hydrogels, contact lenses, inserts
-Know how to make figures/flowcharts 
-Ideally have a PhD or MSc degree
-Write well in English 
-Availability for the next two weeks to work on the article

Application deadline: December 25th at 11:59pm EST
Selected candidates will be contacted for an interview. 
If interested, please send me an email at wuyangkevin1@hotmail.com with your CV emphasizing your academic background, past peer-reviewed publications and research projects. Other details (e.g., community service, awards/scholarships) can be omitted.

p.s This paper will be published in a peer-reviewed journal (IF 6.52), and the publication is almost guaranteed, since we were directly invited by the editor to write the article.

The use of biodegradable polymeric drug delivery systems in the treatment of ocular diseases

Michael Verret

Our study goal is to conduct a scoping review that will describe clinical trials evaluating the impact of pharmacologic intraoperative opioid minimization practices on patient-centred outcomes and identify promising pharmacologic intraoperative opioid minimization strategies. This scoping review will identify knowledge practice gaps, inform future research, and summarize clinical and methodological strengths and limitations.

Intraoperative pharmacologic opioid minimization strategies and patient-centred outcomes after surgery: a scoping review 

Apurva Dixit

Patients with end-stage renal disease&nbsp;are a unique population requiring special attention to drug use and dosing due to significantly altered pharmacokinetics, tendency to polypharmacy, and comorbid risk factors. Many medications are either completely contraindicated, or if used, must be dose reduced to reduce risk of adverse events. Adverse drug reactions (ADRs) are known to lead to emergency room visits, hospitalization, and/or prolonged hospitalization in the general population, but to what extent ADRs contribute to the high admission rates and long lengths of stay in patients with ESRD is uncertain.The purpose of this project is to implement cost-efficient strategies that are embedded into routine clinical practice, involving the entire health care team and patients, in order to reduce the incidence of ADRs.
Aims:
i) To determine the rate of preventable ADRs in ESRD patients over the last 24 months at the MUHC resulting in emergency room visits, hospitalization, or prolonged length of stay.
ii)&nbsp; To identify modifiable risk system-related factors for these ADRs.
iii) To develop and implement tools and strategies addressing these factors in order to reduce rates of hospital ADRs.&nbsp;
&nbsp;

Reducing Preventable Adverse Drug Reactions in Patients Receiving Maintenance Hemodialysis

I am nephrologist and clinical researcher based at the Montreal General Hospital. My research focuses on clinical outcomes in dialysis patients. 
Some of my publications can be found here: https://pubmed.ncbi.nlm.nih.gov/?term=emilie+trinh&sort=date
 
I am currently looking for a medical student to help lead a review on the topic of Indigenous health in patients with end-stage kidney disease.
 
If interested, please contact me at: emilie.trinh@mcgill.ca

Racial inequities among Indigenous patients with end-stage kidney disease

Pierre Pluye

Ideally, 2 medical students will work together on this project and can publish a paper (contact:&nbsp;<a href="mailto:piree.pluye@mcgill.ca">pierre.pluye@mcgill.ca</a>).
INTRODUCTION
Problem: 60% of the Canadian population faces health literacy issues.
Needs: Clinical organizations must improve access to health-related information in clear and simple languages (legal obligation).
However, the literature on how to plan, implement, assess and sustain Health Literate clinical organizations is sparse.
Thus, the objective is to synthesize knowledge on these issues.
METHODS
Design: Systematic mixed studies review (including qualitative, quantitative and mixed methods studies)
Specific questions: In clinical settings, e.g. a GMF or a CLSC, how to (Q1) plan, (Q2) implement, (Q3) evaluate, and (Q4) sustain a Health Literate organization?
Eligibility criteria: TBD with the supervisor and GMF representatives (clinicians, managers, and paptient partners)
Sources of documents: TBD with a librarian.
Search strategy: TBD with a librarian.
Identification and selection of documents: 2 independent reviewers using RYYAN.
Critical appraisal: 2 independent reviewers using the MMAT.
Synthesis: 2 reviewers using thematic analysis.
EXPECTED RESULTS
A "Health Literate Organization" plan for McGill GMFs will be established with the GMF representatives.
A publication.
&nbsp;

Health Literate clinical organizations (planning, implementation, evaluation, and sustainability): a systematic mixed studies review (including qualitative, quantitative and mixed methods studies)

emilie.trinh@mcgill.ca

Single center quality improvement project examining the trajectory of advanced care directives in patients with end-stage kidney disease on hemodialysis.

Trajectory of advanced care directives in patients with end-stage kidney disease 

Amir Razaghizad

The aim of this project is to provide an overview and evaluate the effectiveness of artificially-intelligent interactive voice response (AI-IVR) technologies that use a natural spoken language input for the purposes of diagnostic screening of a disease, focusing on their clinical applications, digital reliability, and diagnostic accuracy.  

Intelligent Interactive Voice Response Systems For Disease Screening in Healthcare: A Scoping Review 

Kevin Yang Wu

<div class="MuiPaper-root MuiPaper-outlined MuiPaper-rounded css-1r6cvrw">
Our review paper will be on retinal prosthesis/artificial retina (i.e. bionic eyes). This paper will be published in a peer-reviewed journal (IF 3.85), and the publication is almost guaranteed, since we were directly invited by the editor to write the article.
Our&nbsp;review&nbsp;paper will be on the use of retinal implantable sensors and devices in assisting patients with severe retinal degeneration. This will be a technology-oriented paper, focusing on&nbsp;materials and device technologies. Therefore those with a background in engineering are welcome.
Selection criteria:
-Past experience in engineering research. Here are some examples of papers similar to our review article:&nbsp;
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350159/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350159/</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/31486609/">https://pubmed.ncbi.nlm.nih.gov/31486609/</a>
<a href="https://www-ncbi-nlm-nih-gov.ezproxy.usherbrooke.ca/pmc/articles/PMC6761377/">https://www-ncbi-nlm-nih-gov.ezproxy.usherbrooke.ca/pmc/articles/PMC6761377/</a>
-Knowledge of the following keywords: Implantable electronic devices, flexible sensors/actuators, human&ndash;machine interface, photovoltaic, tissue electronics
-Know how to make figures/flowcharts&nbsp;
-Write well in English&nbsp;
&nbsp;
If interested, please send me an email at&nbsp;<a href="mailto:wuyangkevin1@hotmail.com">wuyangkevin1@hotmail.com</a> with your CV emphasizing your academic background, past peer-reviewed publications and research projects. Other details (e.g., community service, awards/scholarships) can be omitted.
&nbsp;
Happy Holidays!
-K.Y. Wu, MD, DMD
<a href="https://www.linkedin.com/in/kevin-yang-wu-md-dmd-5ab5a2b1/">https://www.linkedin.com/in/kevin-yang-wu-md-dmd-5ab5a2b1/</a>
</div>

The use of retinal implantable sensors and devices in assisting patients with severe retinal degeneration

Shaifali Sandal

My research group and I are conducting multiple projects in the field of kidney transplantation and kidney donation. Our projects use mixed methods and I currently have ongoing qualitative studies, scoping and systematic reviews, survey studies, etc.

A scoping review and a survey study

Mallory Downie

Nephrotic syndrome is the most common cause of kidney disease in children worldwide, with up to 3000 Canadian children newly diagnosed each year. Most children respond to first-line treatment with corticosteroids and are labelled as having steroid sensitive nephrotic syndrome (SSNS). There is enormous phenotypic variability in SSNS, ranging from an isolated episode to a severe relapsing course to dependence on ongoing immunosuppression to maintain remission; the cause of this variability is largely unknown and I hypothesize that genetic determinants play a role. In this project, I will correlate the specific clinical features of SSNS in 749 children with their genetic variants by (broadly) using linear regression analysis. This study will determine if there are genetic variants that can predict SSNS phenotype, which will then allow us to risk stratify patients with SSNS to optimize treatment regimens.&nbsp;
For this project, the applicant will be required to collect the specific clinical information from my database of children with SSNS. This would include demographic information, number of disease relapses, medications and dosages, time to remission during initial episode, etc. I will later use this information to relate it to the genetic information collected on the same children.&nbsp;
&nbsp;

Identify the genetic variants associated with specific clinical features of steroid sensitive nephrotic syndrome in children

Our review paper will be on retinal prosthesis/artificial retina (i.e. bionic eyes). This paper will be published in a peer-reviewed journal (IF 3.85), and the publication is almost guaranteed, since we were directly invited by the editor to write the article.
Our&nbsp;review&nbsp;paper will be on the use of retinal implantable sensors and devices in assisting patients with severe retinal degeneration. This will be a technology-oriented paper, focusing on&nbsp;materials and device technologies. Therefore those with a background in engineering are welcome.
Selection criteria:
-Past experience in engineering research. Here are some examples of papers similar to our review article:
<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350159/">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350159/</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/31486609/">https://pubmed.ncbi.nlm.nih.gov/31486609/</a>
<a href="https://www-ncbi-nlm-nih-gov.ezproxy.usherbrooke.ca/pmc/articles/PMC6761377/">https://www-ncbi-nlm-nih-gov.ezproxy.usherbrooke.ca/pmc/articles/PMC6761377/</a>
-Knowledge of the following keywords: Implantable electronic devices, flexible sensors/actuators, human&ndash;machine interface, photovoltaic, tissue electronics
-Know how to make figures/flowcharts
-Write well in English&nbsp;
&nbsp;
If interested, please send me an email at&nbsp;<a>wuyangkevin1@hotmail.com</a> with your CV emphasizing your academic background, past peer-reviewed publications and research projects. Other details (e.g., community service, awards/scholarships) can be omitted.
&nbsp;
Happy Holidays!
-K.Y. Wu, MD, DMD
<a href="https://www.linkedin.com/in/kevin-yang-wu-md-dmd-5ab5a2b1/">https://www.linkedin.com/in/kevin-yang-wu-md-dmd-5ab5a2b1/</a>

Camille Tessier

Bonjour &agrave; tous!
&nbsp;
Je suis &agrave; la recherche d'un externe (ou r&eacute;sident junior) pour participer &agrave; mon projet de recherche sur les leuc&eacute;mies plasmocytaires (PCL). L'objectif du projet est de mieux caract&eacute;riser cette maladie tr&egrave;s rare et d'essayer de comprendre pourquoi certains patients avec un my&eacute;lome se transforment en PCL.
&nbsp;
Il s'agit d'un projet r&eacute;trospectif multicentrique, qui implique 8 h&ocirc;pitaux universitaires, dont le Jewish General Hospital. Je suis donc &agrave; la recherche d'une personne pour effectuer la collecte de donn&eacute;es dans cet h&ocirc;pital. Comme je suis r&eacute;sidente en h&eacute;matologie &agrave; Sherbrooke, je n'ai aucun acc&egrave;s au syst&egrave;me informatique de McGill. La personne qui effectuera la collecte de donn&eacute;e doit donc absolument avoir ses propres codes d'acc&egrave;s et &ecirc;tre autonome avec l'utilisation du syst&egrave;me informatique du JGH.
&nbsp;
L'implication requise est tr&egrave;s courte puisqu'il n'y a que 8 patients &agrave; collecter (temps total &lt; 10h).&nbsp;
&nbsp;
Si vous &ecirc;tes int&eacute;ress&eacute; ou si vous avez des questions, n'h&eacute;sitez pas &agrave; me contacter!
&nbsp;
---------------------
&nbsp;
Hello everyone!
&nbsp;
I am looking for an 3rd or 4th year med stutent (or junior resident) to participate in my research project on plasma cell leukemia (PCL). The objective of the project is to better understand this very rare disease and to try to understand why some patients with multiple myeloma transform into PCL.
&nbsp;
This is a multicentre retrospective project, which involves 8 teaching hospitals, including the Jewish General Hospital. I am looking for a person to carry out data collection in this hospital. As I am a resident in hematology in Sherbrooke, I have no access to the McGill computer system. The person who will carry out the data collection must absolutely have his own access codes and be autonomous with the use of the JGH computer system.
&nbsp;
The involvement required is very short since there are only 8 patients (total time &lt; 10h).
&nbsp;
If you are interested or have any questions, please do not hesitate to contact me!

Projet de recherche en hématologie maligne / Research project in malignant hematology

Todd Lee

We conduct research with trainees in a variety of areas, usually thematically aligned with their interests.&nbsp; Projects can range in size and scope and can be synthesis based (e.g., narrative or systematic review), observational (working with data sources including pre-existing databases) and/or bench microbiology projects.&nbsp; We also conduct randomized controlled trials and have a funded clinical trials fellowship for trainees who already have an independent practice licence.
Some examples of trainee publications from our lab include:
Evaluations of diagnostic tests:
<a href="https://pubmed.ncbi.nlm.nih.gov/34464734/">https://pubmed.ncbi.nlm.nih.gov/34464734/</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/32479781/">https://pubmed.ncbi.nlm.nih.gov/32479781/</a>
Evaluations of various treatments:
<a href="https://pubmed.ncbi.nlm.nih.gov/35944134/">https://pubmed.ncbi.nlm.nih.gov/35944134/</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/36632358/">https://pubmed.ncbi.nlm.nih.gov/36632358/</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/33894072/">https://pubmed.ncbi.nlm.nih.gov/33894072/</a>
Conduct of controlled trials and prospective observational cohorts:
<a href="https://pubmed.ncbi.nlm.nih.gov/32667982/">https://pubmed.ncbi.nlm.nih.gov/32667982/</a>
<a href="https://pubmed.ncbi.nlm.nih.gov/33813124/">https://pubmed.ncbi.nlm.nih.gov/33813124/</a>

Dealing with dogma in infectious diseases and internal medicine

Sonia Michaelsen

<span style="font-size: 11.0pt; line-height: 107%; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">Sexual and gender-based violence (SGBV) is a serious social and public health issue that can lead to negative physical and mental health consequences for individuals and populations. Both males and females within humanitarian crises face an increased risk of SGBV. Due to the civil war in South Sudan, there are currently over 1 million South Sudanese refugees who have fled to Uganda. The goal of this research was to explore and compare the perceptions and experiences of SGBV toward South Sudanese refugees in Uganda who live in designated settlements to those who self-settled. To achieve this goal, mixed methods were used, including Fuzzy Cognitive Mapping, interviews, and household prevalence surveys in 2 urban centers (Gulu and Koboko) and 2 refugee settlements (Pagirinya and Palabek).

Sexual and gender-based violence against south sudanese refugees in Uganda: a mixed methods case study

Alexandra de Pokomandy

I am the director of research at the Department of Family Medicine, McGill University. Many researchers in our department could create an opportunity for medical student(s) interested to explore or gain experience in research. The specific project, tasks, work hours and duration would depend on the student interests, the project and the researcher.

Research in Primary Care

Amro Mohammad 

Dr Diaz team extracted extensive information on 425 patient over 2 years. Details of the table can be offered upon request.&nbsp;
We pubished one manuscript on the effect of dexamethasone use on peri-operative complication (In Press).&nbsp;
Another paper is under review for a survival advantage after metformin use in glioblastoma patients&nbsp;
Third project (help neeeded here!) Wbc count &amp; neutrophils/Lymphocytes ratio and other parameteres with or without Dex use on survival and other outcomes of GBM patients&nbsp;

Dexamethasone-induced leukocytosis in glioblastoma patients

Jorane-Tiana Robert

We conduct several quality improvement in nephrology aimed at improving patient experience and optimizing care.
We are currently conducting studies in the following areas (optimizing time to kidney transplantation, improving transition of care in hemodialysis patients, reducing rates of infections in hemodialysis patients) and have the infrastructure and ressources to conduct other studies as well.
&nbsp;

Quality Improvement Projects in Nephrology

Caroline Najjar

<span style="font-size: 12.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">Renal disease patients should ideally be started on home dialysis when possible, but many patients are started on urgent in-center hemodialysis due to a variety of factors. The goal of this project is to:
<span style="font-size: 12.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">&nbsp;1) characterize the amount of patients started on home vs in-center dialysis 
<span style="font-size: 12.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">2) assess whether vulnerable populations are more at risk for in-center dialysis&nbsp;
<span style="font-size: 12.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">3)&nbsp;show what the barriers are to starting home dialysis
<span style="font-size: 12.0pt; font-family: 'Calibri',sans-serif; mso-ascii-theme-font: minor-latin; mso-fareast-font-family: Calibri; mso-fareast-theme-font: minor-latin; mso-hansi-theme-font: minor-latin; mso-bidi-font-family: 'Times New Roman'; mso-bidi-theme-font: minor-bidi; mso-ansi-language: EN-CA; mso-fareast-language: EN-US; mso-bidi-language: AR-SA;">4) describe where resources could be invested to specifically help vulnerable populations have better outcomes

Dialysis in Vulnerable Populations

Ivan Sarmiento

How a person is classified can affect their behaviour and decision-making. Social media is a major source of information that many people use to classify their health conditions. This could lead to increased health literacy with positive effects in early recourse for proper treatment or conflictive repercussions such as cyberchondria, sociogenic illnesses, fear and anxiety.
This is still an unexplored field. A scoping review on cyberchondria reported in 2021 that measures of this issue are still underdeveloped, and understanding its causal mechanisms requires further conceptualization.
This systematic review will explore empirical studies evaluating the effects of social media on self-perceived health status.

What is the effects of social media on self-perceived health status?

Emilie Trinh

Quality improvement project on the implementation of an incremental (2X/week) hemodialysis protocol from Nov 1 2022 to October 31 2024 at the Montreal General Hospital.
&nbsp;